Kokab Jabeen, Fareeha Imran, Saima Inam, Aasma Noveen Ajmal, Saira Zafar.
Impact of dengue virus on hematological and biochemical parameters in dengue patients reporting to a tertiary care setting.
J Allama Iqbal Med Coll Jan ;19(4):949-55.

Background: This study reveals clinical manifestation and alterations in hematological and biochemical parameters in connection to spectrum of severity of dengue fever (DF), dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). Methods: The study was conducted on seropositive cases of dengue at Jinnah Hospital Lahore (tertiary care hospital) from January to December 2018. Patients were divided into three groups (DF, DHF and DSS) per criteria of world health organization (WHO). Results: The frequency of various symptoms and alterations in hematological and biochemical parameters were compared between patients with classic DF and patients with complicated form of dengue disease as DHF and DSS. Total 345 patients those visited with suspected dengue illness, 108 (31.3%) patients were serologically confirmed for dengue infection. Out of 108 seropositive cases, patients were classified as classical DF- 81(75%), DHF- 22(20.4%) and DSS -5 (4.6%). Mean age was 32.3±12.4 years, with male 80 (74%) and female 28 (25.9%). Conclusion: Common symptoms for dengue were fever and headache (100%), arthralgia (82%), myalgia (80.5%), retro-orbital pain, (68.5%), vomiting (48%) and bleeding tendencies (38%).

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