Waleed Shahzad, Muhammad Hassan, Haris Majid Rajput, Tehmina Inayat, Naveed Ullah Khan, Mazhar Badshah.
A Rare Case of Epilepsia Partialis Continua Secondary to Rasmussen\\\'s Encephalitis.
Pak J Neurological Sci Jan ;16(4):31-4.

Rasmussen`s encephalitis is a rare baffling disorder seen in nearly 1 % to 2 % of epilepsy population and in 7.4% of paediatric population. It is mostly seen in children and in most cases seizures are seen during 14 months to 14 years with peak age 3 to 6 years. Etiology includes viral infections, humoral autoimmunity and T-cell mediated cyto-toxicity of the brain tissue. The main clinical features are intractable epilepsy, hemiparesis, hemidystonia, hemiathetosis, epilepsia-partialis-continua and mental decline. Imaging shows unilateral hemispheric brain atrophy. Here we describe a unique case of a 15-year-old Pakistani girl with severe immune mediated brain disorder characterized by unilateral hemispheric atrophy, progressive neurological dysfunction and intractable seizures. Literature on Rasmussen`s encephalitis following is sporadic with very few publications. This clinical entity should be kept in mind when a patient presents with intractable refractory seizures. Early recognition and treatment is beneficial to prevent adverse outcomes.

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