Asif Hussain.
Clinicopathological Aspects and Management of Psoriasis.
J Pak Society Int Med Jan ;3(3):201-9.

Psoriasis is a common rheumatological disease worldwide. It has many articular and extra-articular complications associated with comorbidities and mortality. It's often confused with other joint diseases such as rheumatoid arthritis. Also, various patterns of Psoriasis involving skin and joints make it a clinical puzzle that can mimic many diseases and pose a great difficulty for the diagnosis. Cutaneous and rheumatological complications contribute the most to morbidity and mortality and pose great difficulty managing Psoriasis. Though the advancement in the treatment of psoriasis arthritis has improved many articular complications, it has also increased the risk of many complications such as infections and drug-related oxicities. Recently there has been development in treating psoriatic arthritis and other seronegative arthritides, which are very different from those used for rheumatoid arthritis. It's important to understand these differences for managing patients with psoriatic arthritis, which almost every doctor sees. This review article aims to provide insight into the thogenesis of Psoriasis, its various manifestations, and its management in light of recent evidence.

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