Sana Rasheed Chaudhry, Zunnera Rashid Chaudhry, Komal Iqbal, Erum Rashid Chaudhry, Hifza Noor Lodhi, Samita Yasmin, Muniza Saeed.
Serum ischemia modified albumin levels in diabetic retinopathy.
Pak Postgrad Med J Jan ;30(02):87-9.

Background. This study was planned determine and compare the levels of ischemia modified albumin in controls and diabetic patients with and without retinopathy. Materials and Methods: Diabetic Clinic of Lahore General Hospital was selected the conduction of the study in collaboration with an opthalmologists from September 2014-May 2015. 60 subjects of either sex were chosen and were separated into 3 groups with 20 subjects in each group. Group 1 was of normal healthy controls, group 2 of diabetics without retinopathy and group 3 of diabetics with retinopathy. Diabetic retinopathy was diagnosed by an ophthalmologist by an indirect method using a 90D lens on slit lamp examination, and IMA levels were determined by rapid calorimetric method. Results: The median (IQR) of serum levels of IMA in three groups were 0.51(0.43-0.54) in group I, 0.59(0.53-0.61) in group II and 0.63(0.59-0.71) ABSU .A significantly higher IMA levels in diabetics with retinopathy were seen as compared to diabetic without retinopathy and control with a p value of 0.00 respectively. Conclusion: Our study concludes that serum IMA levels raise as the diabetes progresses in its complications.

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