Madiha Iqbal, Shazia Rizwan, Anum, Muhammad Shahid Ghaffar, Hina Mehmood, Maria Imdad, Sana Imdad.
Comparison of early versus delayed cord clamping in neonates born at term in a tertiary care hospital.
Pak J Surg Jan ;37(3):220-4.

Introduction: Prevention of iron deficiency in infancy may promote neurological development. Delayed cord clamping can prevent iron deficiency during the first 6 months of life. Very limited data is available on impact of timing of cord clamping on infant development in the early years of life. Objective: To compare the mean IgG levels and Ages and stages questionnaires (ASQ) score of early versus delayed cord clamping in neonates born at term in a tertiary care hospital Material and Methods: A randomized clinical trial was done at the Department of Pediatric Medicine, Services Hospital, and Lahore during period from 1st June 2019 till 30th June 2020. A total of 220 patients fulfilling the inclusion criteria were included in the study in group A, cord was clamped early and in group B, cord was clamped delayed. Then all patients had undergone delivery. After 4 months, blood sample of neonate was obtained for assessment of IgG level. ASQ score was assessed by researcher herself and noted. Results: IgG level and ASQ score was compared at 4th month in term neonates who underwent early and delayed cord clamping. Results of this study showed that IgG level and ASQ score did not show statistically significant difference in neonates in both study groups. i.e. IgG level: Group-A: 3.13 vs. Group-B: 3.27, p-value=0.303 & ASQ score: Group-A: 255.15 vs. Group-B: 258.57, p-value>0.05. Conclusion: There was insignificant difference in IgG level and ASQ score in term neonates up to 4 months of age who underwent early and delayed cord clamping.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com