Shazia Shaheen, Fatima Chaudhry, Muhammad Umar, Shagufta Noor, Tehmina Hassan, Noor Abid.
Diagnostic Accuracy of Endometrial Thickness in Diagnosing Endometrial Hyperplasia by Taking Endometrial Sampling as the Gold Standard in patients with Post-Menopausal Bleeding.
Annals Punjab Med Coll Jan ;16(2):136-9.

Background: Endometrial hyperplasia is most common with post-menopausal bleeding (PMB). The clinical tests to evaluate the endometrium include transvaginal ultrasound scanning (TVS) to measure endometrial thickness (ET) and endometrial sampling (ES) with hysteroscopy as gold standard. Objective: To determine diagnostic accuracy of endometrial thickness in diagnosing endometrial hyperplasia by taking endometrial sampling as the gold standard in patients with post-menopausal bleeding. Study Design: Cross-sectional study. Settings: Department of Obstetrics & Gynecology, Allied & DHQ Hospitals affiliated with Faisalabad Medical University, Faisalabad Pakistan. Duration: January 01, 2022 till March 31, 2022. Methods: A total of 150 patients fulfilling the inclusion criteria were recruited. Endometrial sampling was obtained by using a pipelle sampler. Patient’s characteristics taken into account were age, parity, body mass index, hypertension and diabetes. Histological findings were compared to measure the diagnostic accuracy of endometrial hyperplasia. Results: The mean age of patients was 55.29 ± 2.91 years with minimum and maximum age as 50 and 60 years. Endometrial hyperplasia was diagnosed in 67(44.7%) females on sampling and in 71(47.3%) females on endometrial thickness by USG. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of endometrial thickness was 82.09%, 80.72%, 77.46%, 84.81% and 81.33%. Conclusion: It is concluded that endometrial thickness is useful for diagnosis of endometrial hyperplasia in females with post-menopausal bleeding and used even in low source settings as ultrasonography requires basic ultrasound knowledge.

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