Umar Noor, Toheed Ahmed, Saliha Khalid, Maryam Khalid, Ammara Sharif, Isra Noor, Warda Waheed, Ishmal Jamil, Zainab Sameen Zafar, Umme Kulsum.
Nano-drug designing strategies and targeted applications for cancer treatment.
Int J Pharm Integrated Health Sci Jan ;4(1):68-87.

Introduction: Recent medical improvements have not much of an influence on cancer patients` life expectancy throughout the world. Nano medicine is a cutting-edge topic in cancer therapy, with various well-tested techniques for delivering drugs. Objectives: Liposomes and other nanostructures are often used in therapeutic contexts and scientists in numerous countries are currently investigating polymer micelles. These structures will become more lucrative if they include chemicals that help with site-specific delivery and tailored release. The objective of the current review is to provide comprehensive information on nano-drugs. Methods: Liposomes, polymer micelles, and dendrites, among other well-known nanoparticle technologies, can be controlled and regulated to generate a more long-lasting and effective non-therapeutic modality. Occasionally, the term "multistage drug delivery" is used. This method, which employs a well-designed Nano-carrier, overcomes several biological barriers to medicine delivery. Results: Several multistage drug delivery system papers were reviewed for this study and their advantages were discussed with some pharmaceutical drug examples as well. Conclusions: We emphasize developments in nanoparticle design that overcome heterogeneous delivery barriers and contend that intelligent nanoparticle design can boost effectiveness in general delivery applications especially cancer treatment while enabling customized designs for precision applications, ultimately improving patient outcomes.

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