Nehel Raza, Zunaira Arshad, Saira Riaz, Noshi Ilyas, Asma Masood, Kiran Irfan, Muhammad Khalil-ur Rehman, Tahir Jamil Ahmad, Shahbaz Aman.
The Estimation of Serum 25(OH) D (Vitamin D ) levels in Atopic Dermatitis patients.
J Pak Assoc Derma Jan ;33(3):902-5.

Background Atopic dermatitis is an itchy dry skin problem commonly present in children. The evaluation of vitamin D level in atopic patients with regular supplementation can help to improve disease outcome and prognosis. Objective:  To find frequency of serum 25(OH) D (vitamin D) level in patients of atopic dermatitis. Methods: This cross sectional study was performed at Mayo Hospital Lahore, dermatology facility, over a period of 6 months. A total of 95 clinically diagnosed cases of atopic dermatitis (AD) meeting inclusion criteria were enrolled after taking informed consent. All basic demographical data and other contact details were taken from each patient. Blood samples were taken from the antecubital veins and were sent to hospital laboratory for the measurement of serum 25(OH) D levels. Results:  The mean age of cases was 21.93 ± 13.02 years with minimum and maximum age as 1and 45 years. There were 51 male and 44 female cases. The mean body mass index (BMI) was 25.39±3.62 with minimum and maximum BMI as 20.10 and 32.70. The mean serum vitamin D level was 31.26±13.85ng/ml with minimum and maximum serum vitamin D level as 15.20 and 54.90ng/ml. There were 44 (46.3%) cases who had serum level of vitamin D <20ng/ml and 51(53.7%) cases had serum level of vitamin D ≥20ng/ml. Conclusion: It is concluded that frequency of serum vitamin D level <20ng/ml was seen in 46.3%. Hence in patients of atopic dermatitis vitamin D levels should be checked and if found low then vitamin D supplementation must be given additionally. This additional supplementation will help patients to reduce the severity of the disease and better prognosis of standard care. Keywords: Serum, vitamin D, low levels, atopic dermatitis                        

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