Rubina Aman, Jamal Zafar, Farida Tahir.
Type-2 Diabetes Mellitus in the light of UKPDS.
J Pak Inst Med Sci Jan ;14(2):810-5.

Majority of the diabetic population consists of the type-2 diabetes mellitus. It is a complicated syndrome and in addition to hyperglycaemia there is an array of micro vascular and macro vascular complications. The issue of optimal management of type-2 diabetes has remained unanswered. The United Kingdom Prospective Study is the largest trial that evaluates various therapeutic modalities in their ability to control blood glucose and prevent the dreaded micro and macro-vascular complications of D.M. The results of this study have been published in various issues of BMJ, THE LANCET, NEJM & Annals of Internal Medicine. Papers of the UKPDS group have been carefully studied and the important practical implications highlighted in this review.

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