Shumaila Shahzeen, Khalid Mehmood Awan, Amna Khalid, Mohsin Ali, Mehwish Ejaz, Khanda Fishan Mumtaz.
Clinical profile of dengue infection in pediatric age group at Social Security teaching hospital, Lahore.
Pak Postgrad Med J Jan ;34(3):145-9.

Background: Dengue viral infection is a significant tropical disease and have become a major global public health concern. Objective: Tosketchthe evolving clinical spectrum of dengue especially highlighting the unusual manifestations.Methods:Data of 120 suspected dengue fever cases was collected, compiled, and analysed during the monsoon and post-monsoon seasons in the year 2021 at the Department of Pediatric Medicine, Social Security Teaching hospital,Lahore.Patients with serological confirmation of dengue infection were classified according to DengueGood Clinical Practice(GCP)Guidelines 2020. Clinical parameters were studied. Results: Out of 120suspected patients with Dengue fever enrolled in the study, 48 (40%) had serologically confirmed dengue infection. Out of 120 cases, 68 (56.66%) patients were males and 52(43.33%) were females. 66.66% patients had classical dengue fever while 33.33% had dengue hemorrhagic fever. DHF grade I/II was seen in 25% cases and grade IIIDHF in 8.33% The most common symptoms afterfever were vomiting (85.4%), abdominal pain (68.75%), headache(37.5%), rash (20.83%)and itch (16.66%). Hemorrhagic manifestations were observedin 43.75% of patients. Atypical manifestations were documented in 4 patients (8.33%) patients. Overalloutcome in this study was good with no mortality.Conclusion:Dengue infection has poseda huge burdento the health-caresystem with spectrum ranging from mild self-limiting diseaseto severe fatal disease. It usually presents with common manifestations as shown by this study but may also have varied and multi-systemic manifestations like encephalitis and acute respiratory distress syndrome which may go unnoticed. Pediatricians should have a high index of suspicion for atypical manifestations so revelation of the exact clinical profile is significant for patient effective management.

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