Fatima Khalid, Mariam Danish Iqbal, Tariq Mahmud Tariq, Naureen Saeed, Safana Sadaf, Asma Akhtar.
Antibiogram of staphylococcus aureus among clinical isolates at a tertiary care hospital in Lahore.
Pak Postgrad Med J Jan ;34(3):135-8.

Background: Staphylococcus aureus has become an important cause of persistent nosocomial acquired infections. Consequently,it hasbecome a global health concern. It has an uncanny ability of evolving means of resistance tocommon antimicrobial agents.Management of hospital-acquired infections is complicated by the worldwidespread of Methicillin Resistant Staphylococcus aureus (MRSA)in the modern day. Objective: This study was conducted to screen and assess the antibiotic susceptibility pattern of Staphylococcus aureus(S. aureus) from different hospital specimens and determining prevalence of methicillin-resistant Staphylococcus aureus(MRSA).Methods:This retrospective descriptive study in which data of all clinical isolates reported as S. aureus from 1 November 2019 to 31 October 2020 was collectedthrough the electronic medical recordssystem of Shalamar Teaching Hospital. Record of antibiotic susceptibility profile wascategorized and analyzed. Results:During the mentioned period (1st November 2019 to 31st October 2020), 149 total isolates of S.aureus were reported. Out of those isolates4.7% were sensitive to Ampicillin, 20% to Ciprofloxacin, 51% to Clindamycin, 40% to Cefuroxime, 14%to Erythromycin, 64%to Fusidic Acid, Fosfomycin showed 6.0%sensitivity, Nitrofurantoin 89%, Cefoxitin 45.0%, Gentamicin72.5%, Linezolid 100%, Co-trimoxazole 33%, Teicoplanin 100%, and Vancomycin 100%.Conclusions:According to this study Vancomycin, Teicoplanin and Linezolid are still the mostappropriatedrugs that could be chosen forthetreatment of S. aureusinfections, as all isolates show 100% susceptibility to these antibiotics.

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