Mian Anwar Zeb, Muhammad Usman, Farooq Khan, Siyab Ahmad, Liaqat Ali, Adnan Badar.
To Determine the Effectiveness of Conservative Treatment Versus Appendectomy in the Management of Acute Uncomplicated Appendicitis.
J Saidu Med Col Jan ;14(1):19-23.

Background: The vermiform appendix is considered to be a vestigial organ by the most. Its importance in surgery results only from its tendency for inflammation that results in a clinical syndrome known as acute appendicitis. It is the most common indication for emergency abdominal surgery in patients with acute abdomen with a crude annual incidence of 26 per 10,000 populations. Objectives: To determine the effectiveness of Conservative Treatment Versus appendectomy in the management of Acute Uncomplicated Appendicitis. Material and Methods: This randomized control trial was conducted in Department of General Surgery Saidu Group of Teaching Hospital Saidu sharif, from 1st January 2022 to 31st December 2022. A total of 96 cases were enrolled, that were divided into two groups. Informed written consent was taken from each patient. Patients in Group A were subjected to non-operative management with antibiotics while patients in Group B were subjected to appendectomy. Patients in both groups were evaluated for various parameters such as age, gender, pre- and post-operative duration of pain (group B), Alvarado score. Post stratification chi-square test was applied keeping P Value < 0.05 as significant. Results: Mean and SD for Age, Duration of Stay, Pre & Post Treatment Abdominal Score and Pre and Post Treatment Alvarado Score in Group A was recorded as 35+-10.60, 3.0+-0.24, 7.0+-0.49, 3.0+-0.20, 9.0+-0.41 and 3.0+-1.62 respectively. In the same manner, Mean and SD for Group B was 35+-12.53, 5.0+-0.41, 7.0+-0.35, 3.0+-0.35, 3.0+-0.20, 9.0+-0.41, and 2.5+-1.5, respectively. Success rate in Group A was 26 (52%) whereas in Group B it was 36 (72%) patients. Conclusion: Conservative treatment can be applied safely in the majority of cases of the first attack of uncomplicated acute appendicitis, therefore, avoiding appendectomy and its associated morbidity and mortality. Keywords: Acute appendicitis, Alvarado Score, Antibiotic treatment, Acute uncomplicated appendicitis, Success rate.

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