Naheed Khattak, Sara Jamal, Sundas Ali, Huma Abdul Shakoor, Sana Syed, Samina Tufail Amanat.
Frequency of the appropriate use of platelet concentrates in a tertiary care hospital.
Pak J Pathol Jan ;33(4):114-8.

Objective: The objective of the study was to determine frequency of the appropriate use of platelet concentrates in a tertiary care hospital. Material and Methods: It was a descriptive cross-sectional study that was conducted in Department of Pathology, Pakistan Atomic Energy Commission (PAEC) General Hospital, Islamabad for a period of six months from 1st January to 30th June 2021. Patients of both genders, above five years of age receiving platelets transfusions during the study period were included in this study. An informed consent was obtained from the patients. The data was collected on a predesigned form that included patient demographic and clinical details. All patients were categorized whether the platelet transfusion was appropriate or inappropriate according to the mentioned definitions. To control confounding effects of various factors and to avoid bias in the study, the exclusion criteria were strictly followed. t test was applied to find statistical difference between appropriate and inappropriate transfusions. Results: Out of total 331 patients, 169 (51%) were females while 162 (49%) were males, male: female ratio being 1: 1.04. Mean age was 41.75 + 23.1 years with a range of 6-92 years. Maximum patients were in 31-40 years age group. Single donor platelet units were transfused to 55(16.6%) patients while rest 276 (83.4%) patients received random donor platelets. 301 (90.9%) had appropriate transfusion while 30 (9.1%) patients received blood transfusion due to inappropriate indications. (p <0.0001). Conclusion: From this study it was concluded that a significant number of patients in hospital setting receive inappropriate platelet transfusions.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com