Hafeezullah, Mazhar Hussain, Sohail Aziz, Muhammad Aslam.
Significance of Atrial Natriuretic Peptides in morphological changes in Athlete`s heart.
Pak Armed Forces Med J Jan ;54(1):106-12.

The top-level training is often associated with morphological changes in the heart, including increased left ventricular (LV) cavity dimension, wall thickness, and mass, frequently known as "athlete`s heart”. In regularly trained healthy subjects, both isotonic and isometric exercises produce Physiological hypertrophy of the heart manifested by modifications in ventricular chambers and enhancement of cardiac performance, to sustain tremendous increase in cardiac output during exercise. It has been documented that dimensional changes affect all cardiac cavities to the same extent and result in a balanced cardiac hypertrophy which is a beneficial adaptation to enable the athlete to perform more work. This is a review article.

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