Muhammad Shafique, Khawaja Muhammad Fayyaz, Shafqat Nazir, Mukhtar Ahmad, Mushtaq Ahmed, Abdul Karim.
Diabetes Mellitus; role of magnesium.
Professional Med J Jan ;9(3):191-6.

OBJECTIVE: To study the effects of magnesium supplementation on electrolytes homeostasis, lipid profile and metabolic control. DESIGN: twenty-six non-insulin dependant diabetic patients before and after two months magnesium administration orally. SETTING Patients selected from OPD Medical Units, B. V. Hospital, Bahawalpur. PERIOD: 1998 to 2000. SUBJECTS: 26 no insulin dependant diabetic patients of both sex, age-ranged 40-80 years. METHODOLOGY: Various biochemical kit methods used by spectrophotometery, serum calcium and magnesium were analyzed by atomic absorption spectrophotometer. RESULTS: Serum Mg and Ca levels were found to be lower significantly in diabetic patients as compared to controls. But after magnesium supplementation, these levels were sufficiently increased. Clinically, lipids levels and metabolic control! Glucose and HbAlc) were improved significantly along with anti-diabetic therapy. CONCLUSIONS: Magnesium supplements to the NIDDM patients have beneficial effects on electrolyte metabolism as well as overall metabolic homeostasis.

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