Faisal Hanif, Muhammad Nadeem Aslam, Abdul Majeed Chaudhry.
Single dose versus three doses of Metronidazole in Appendicectomy.
Professional Med J Jan ;9(1):21-3.

In acute appendicitis role of single dose metronidazole, as prophylaxis still needs appreciation where, 1X re is no complication such as perforation or abscess formation. A prospective study of fifty patients is presented who presented with acute appendicitis in the Department of accident and emergency Mayo Hospital, Lahore. They were divided into two groups A & B, 25 patients in each group. Group A was given single dose of metronidazole as prophylaxis preoperatively. Patients in group B received three doses of metronidazole: one preoperatively and two postoperatively. Results were same in both groups, with no postoperative wound infection or intraperitoneal sepsis. Single dose metronidazole proved to be as effective as three doses for in appendicectomy.

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