Haroon Mansur, Faisal Hanif, Muhammad Afzal Sheikh.
Peutz Jeghers syndrome; the polyp may be malignant.
Professional Med J Jan ;9(1):78-80.

Peutz-Jeghers syndrome is an uncommon disease. A case of 9 years old girl is presented who had signs and symptoms of subacute intestinal obstruction. She had mucocutaneous pigmentation of mouth and lips as well. Laparotomy revealed irreducible ileoileal intussusception with a polyp as lead point. Histopathological examination of the polyp showed malignant change. The polyps of Peutz-Jeghers syndrome had the reputation of being hemartomas but lately, cases have been reported of malignant changes in them. Literature has been reviewed to reassess the management of these cases due to increasing evidence of malignancy.

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