Muhammad Anwar, Owais Hameed, Munawar Farooq, Mansoorul Haq, Muhammad Ali Bukhari.
Local anesthetics infiltration in wounds.
Professional Med J Jan ;12(1):69-73.

Objective: To compare the effects of analgesia with local infiltration of bupivacaine in postoperative wounds with control group, which had no infiltration. Study Design: Prospective comparative study. Setting: At surgical unit-1, Sheikh Zayed Medical College/Hospital Rahim Yar Khan. Period: From 1st July 2003 and 30th June 2004. Material and Method: Two groups of 100 patients each were formed to underwent abdominal surgery during the study. In study group, 0.25% bupivacaine was infiltrated in wound margins before applying skin stitches and results were compared with the control group in terms of post operative pain free interval, mobilization time, average hospital stay and complication rate. Results: In study group, post operative analgesic demand was delayed for 5.3 hours as compared to 2.7 hours in control group. 75mg of total analgesic was used as compared to 175mg in control group and the average mobilization time of patients in study group was 8 hours as compared to 14 hours after operation in control group. Average hospital stay and complication rate were less in study group with only 1 % of patients in study group had transient CNS toxic symptoms due to bupivacaine. Conclusions: Wound infiltration with a local anaesthetic is a simple, safe and effective method to provide early post operative wound analgesia.

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