M Hussain Khan, Syed Humayun Shah.
Incidence of Du in Rh Negative Obstetrics Patients.
J Ayub Med Coll Abottabad Jan ;12(2):29-30.

Background: A small number of persons with Rh-negative blood have red blood cells that are not directly agglutinated by anti D during routine testing for Rh antigen, but that do react when the D-typing test is converted to the indirect antiglobulin test, which is Du test. Cells thus identified are then designated as Du cells. This study was done to assess the incidence of Du Patients in Rh negative obstetrics patients. Methods: A total of 1500 pregnant women were screened for Rh antigen. The red blood cells of the D negative subjects was then tested by indirect method. Agglutination confirmed Du other wise it was confirmed as D (-). Results: Out of the 50 D negative women subjected to the indirect antiglobulin test 6 women were found to have `Du` blood. Conclusions: This reflects a significant percentage of D negative, D in subjects in our obstetrics patients. Therefore utmost care should be taken before labeling a subject D negative.

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