Tazeen Fatima Munim, Shaista Rashid.
Screening for asymptomatic bacteuria in Pregnancy.
J Surg Pak Jan ;10(3):34-7.

Objective: To find out the frequency of asymptomatic bacteuria in pregnant women without any symptoms and to find out the common responsible microorganisms and to know their sensitivity pattern to commonly used antibiotics. Study Design: An observational study. Place & Duration: Obstetrics & Gynecology unit III, Abbasi Shaheed Hospital, from March 2003 to June 2003. Patients and Method: The subjects were from indigent group of population, 250 pregnant women, attending first antenatal clinic were included in the study. Midstream urine of all these women was subjected to urinalysis, culture and sensitivity. Results: The frequency of asymptomatic bacteuria was 7.2%. The most frequent pathogen identified was Escherichia coli (38.89%) followed by enterobacter species (16.68%) and staphylococcus saprophyticus (16.68%). Only one isolate of each of staph aureus, streptococcus agalactiae, proteus mirabilis, serratia marcescens and candida albicans (5.55%) was found. Escherichia coli was found sensitive to gentamycin, nitrofurantion, fosfomycin and quinolones and highly resistant to ampicillin and sulphonamides. Enterobacter species showed sensitivity to gentamycin, ciprofloxacin, norfloxacin, sulphonamides, fosfomycin and resistance for ampicillin, nitrofurantoin and oral cephalosporin. Staphylococcus saprophyticus were found sensitive to carbenicillin, oral cephalosporins, ceftriaxone, fosfomycin, erythromycin, sulphmethoxazole and nitrofurantoin and were resistant to ampicillin, gentamycin and sulphonamides. Sensitivity, pattern reflects that there are a number of antimicrobials available for treatment to which microorganisms are sensitive. An important fact was that these organisms showed resistance for the most frequenly used antibiotics during pregnancy ,that is penicillins and first generation cephalosporins. Conclusion: Culture and sensitivity is must for the diagnosis/screening of asymptomatic bacteuria during pregnancy to avoid maternal and foetal complications.

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