Waseem Yar Khan, Mian Iftikharul Haq, Abdus Samad Khan, Mazhar Khan, Usman Ali.
Frequency of carcinoma in specimens of clinically benign enlarged prostate.
J Surg Pak Jan ;10(4):26-9.

Objective: To determine the frequency of carcinoma prostate on histology, in specimens obtained from patients with clinically benign enlarged prostate. Design: Descriptive study. Place and Duration of Study: This study was carried out in Khyber Teaching Hospital (KTH) Surgical ward D and Lady Reading Hospital (LRH) surgical ward A, Peshawar from January 2004 to December 2004. Patients and Methods: A total of 107 patients who presented to Surgical OPD with bladder outflow obstruction and fulfilled the inclusion and exclusion criteria of the study were included in the study. After an informed consent history, clinically examination and related investigations were carried out. All the patients underwent transvesical prostatectomy (TVP) and their prostate specimens were subjected to histopathology. Results: Total number of patients was 107. Most of the patients (58.88%) with benign prostatic hypertrophy (BPH) were in age range of 56 - 60 years. The common presenting complaints were prostatism (57.94%) and acute retention (34.58%). All patients underwent trans vesical prostatectomy (TVP). On histopathology 3.74% turned out as adenocarinoma prostate while 96.26% biopsies showed BPH. The mean age of presentation with carcinoma (Ca) prostate was 65 years. Conclusion: In this study the frequency of Ca prostate in specimens of clinically benign enlarged gland was 3.74%. Therefore, all specimens must be submitted for histopathology after prostatectomy.

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