Muhammad Dilawar, Aamir Ijaz, Ayesha Hafeez, Nadeem Akbar, Farooq Ahmad Khan, Muhammad Aamir, Masood Anwar, Zahoor Shah.
Pattern of serum protein electrophoresis in various diseases.
Pak J Pathol Jan ;16(1):22-7.

Objective: To determine the frequency and pattern of different clinical disorders on the basis of serum protein electrophoresis (SPE). Design: Descriptive cross sectional study. Place & Duration of Study: The study was conducted at the Department of Chemical Pathology and Endocrinology, Armed Forces Institute of Pathology, Rawalpindi, during May 2003. Material and methods: Five hundred SPE strips (spanning over a period of one year) of patients along-with relevant clinical information were analysed to determine the frequency and pattern of clinical disorders. Results: Out of the 500 strips analyzed, 324 were from males (mean age: 53.5y) and 176 were from females (mean age 51.5 y). Six major patterns were found including chronic inflammation (40.4%), acute phase response (20.8%), nephrotic syndrome (6.8%), paraproteinemia (9.2%), hepatic cirrhosis (0.8%) and normal pattern (21.18%). Conclusion: Chronic inflammatory disease was found to be the most frequently observed pattern.

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