Nadeem Sajjad Raja, Raja Najam Ul Haq, Khalid Abbas Janjua.
Management of vancomycin-resistant enterococci infections.
Infect Dis J Jan ;15(1):13-9.

The incidence of enterococci from clinical sources shows a significant increase with properties of intrinsic resistance to many antimicrobials particularly glycopeptides such as vancomycin. Vancomycin-resistant enterococci (VRE) are usually resistant to many antimicrobials and pose a great threat to the patient safety. The possibility of the transfer of the vanA gene from enterococci to Staphylococcus aureus has caused much concern among scientists and clinicians. Management options for VRE infections are limited. Empirical therapy to treat VRE infections should be guided according to the local antimicrobial susceptibility patterns of VRE. Newly developed antibiotics like linezolid, daptomycin, quinupristin/dalfopristin, have promising effects against VRE. The prudent use of antibiotics, strict guidelines for the use of new antimicrobials, adherence of infection control measures such as surveillance, hand hygiene, environmental disinfection continue to be essential components of the therapeutic management of colonisation and or infection due to VRE. The present study was undertaken to review VRE infections and the therapeutic options for the management of VRE infections. This is a review article.

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