Kausar Aamir, Sibghatullah Sangi, Jamal Ara, Saeed A Mahar, Zulfiquar Rahujo.
A Study of Flouvouxamine in Hospital out Patients with Major Depressive Illness.
J Surg Pak Jan ;6(3):34-6.

A non-comparative study was carried out at the Department of Psychiatry, Chandka Medical College Hospital, Larkana from October 2000 to February 2001. Forty patients between the ages 18 to 60 years, who met the inclusion criteria were registered. Twenty-eight patients completed the study while 12 patients were lost to followup. RESULTS: In the evaluable patient analysis, there was significant improvement seen from baseline in HAMD Rating Scale and CGI for depression. Excellent / Good – 22 (78.5%), Fair – 4 (14.2%) and Poor – 2 (7.14%). Majority (71.4%) of patients showed therapeutic response within dose of 100 to 150 mg/day, while 8 (28.6%) patients required 250 mg/day to achieve response. Most of the patient tolerated the drug well. Side effects were only mild to moderate. Interestingly, no patients had to be withdrawn from the study due to adverse effects or tolerance problem.

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