Adesuwa N Olu Eddo, Chibundu E Ohanaka.
Peripheral lymphadenopathy in Nigerian adults.
J Pak Med Assoc Jan ;56(9):405-8.

Objective: To review the pathology of lymph node disorders in adults with primary peripheral lymphadenopathy. Methods: A 20-year (1985-2004) retrospective study of lymph node biopsies at the University of Benin Teaching Hospital, Benin City, Nigeria. Results: Of the 427 lymph node biopsy specimens received, 238 (55.7%) were from males and 189 (44.3%) from females. Localized lymphadenopathy was observed in 380 (89%) cases. Cervical lymphadenopathy predominated comprising 250 (58.5%) cases. Tuberculosis lymphadenitis and metastatic disease were the major causes of lymph node enlargement constituting 114 (26.7%) and 113 (26.5%) cases respectively. While tuberculosis was commonest in young adult females (15-24 years old) and rare above the age of 45 years, metastatic disease was the predominant cause of lymph node enlargement above 45 years. Non Hodgkin`s lymphoma and Hodgkin`s lymphoma (HL) constituted 69 (16.2%) and 43 (10.1%) cases respectively. HL occurred mostly in young adult males presenting with cervical lymphadenopathy (peak-age = 15-24 years). Non specific lymphadenitis and onchocerciasis comprised 81 (19.0%) and 4 (0.9%) cases respectively. Kaposi`s sarcoma, cat scratch disease and sarcoidosis constituted one case each. Conclusion: The pattern of disease is similar to that of other third world countries (JPMA 56:405;2006).

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