Farooq Ahmed, Farooq Ahmed.
(TIVA) intravenous anesthesia.
Professional Med J Jan ;13(3):341-3.

Objectives To compare the combination of propofol ketamine , propofol fentanyl and propofol vs midazolam for TIVA in terms of haemodynamic changes, analgesia and recovery characteristics. Design A randomized clinical control trial. Setting CMH Rawalpindi. Period. September 2002 to August 2003.Material and Methods. The present study consisted of 75 patients of both sexes between the age group of 18-55 years belonging to ASA grade I and II, who were scheduled for various short surgical procedures. Results. Combination of propofol and ketamine provides better haemodynamic stability throughout the procedure, when compared to propofol fentanyl. Induction time was significantly shorter in the propofol group. Mean recovery time was significantly faster with propofol (12.3 min) compared to midazolam (20.4 min). Conclusion. Combination of propofol and ketamine gives better haemodynamic stability during induction and maintenance of total intravenous anaesthesia. Both propofol and midazolam are safe and effective for TIVA in children. Recovery was faster and more comfortable following propofol

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