Rana Naveed Iqbal, Naseer Ahmad, Junaid Hanif, Khalid Jamal, Syed Abdullah Mazhar.
Mean increase in Pupillary Diameter with Intracameral Injection of 1% Lidocaine and Topical Mydriatic during Phacoemulsification of Cataract Extraction.
Ophthalmol Update May ;14(3):32-5.

Objective: To compare the mean increase in pupil diameter by intracameral injection of 1% lidocaine versus topical mydriatics during phacoemulsification cataract extraction. Materials & Methods: This study was conducted in the Department of Ophthalmology Services Hospital Lahore, from 1st June 2014 to 30th Nov 2014.100 patients suffering from age-related cataract with age range from 50 to 72 years were selected, in which two groups were made on the basis of intracameral lidocaine 1% and topical mydriatics. In Group A, there were 48.0 % (n=24) male and 52.0 % (n=26) female patients while Group B had 44.0 % (n=22) male and 56.0 % (n=28) female patients. Informed consent was obtained from each patient. 100 patients were divided topical and intracameral group. Baseline pupillary diameter was measured 1 hour before surgery in topical group and just before surgery in the intracameral group (D1 ). After that, patients in Group A were given 3 drops of cyclopentolate 1% at 10 minute intervals before surgery for total of 3 doses. Patients in Group B received intracameral 0.3 ml of non preserved lidocaine 1% injected into the anterior chamber at the beginning of surgery. The pupillary diameter was repeated with the same caliper just before surgery in the topical group and 90 seconds after intracameral injection in the intracameral group. (D2 ). Increased in pupillary diameter was measured by subtracting initial diameter (D1 ) from final diameter (D2 ) by same person unaware of study group. Results: Both groups were comparable to each other in terms of age and gender distribution. Mean increase in pupillary diameter was 3.70 + 0.69 mm in mydriatic group and 2.40 + 0.97 mm in intracameral group. (P Value 0.001). Conclusion: There is greater increase in mean pupil diameter by topical mydriatics than intracameral injection of 1% lidocaine during phacoemulsification cataract extraction.

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